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A new theory suggests that criticality a sweet spot between order and randomness is the secret to learning, memory, and adaptability.
When brains drift from criticality, diseases like Alzheimer's can take hold.
Detecting and restoring criticality could transform diagnosis and treatment.
The criticality framework offers a new perspective for understanding neurological disease.
Tau protein buildup in Alzheimer's directly disrupts criticality, Hengen says.
The link between criticality and Alzheimer's opens exciting diagnostic possibilities.
Sleep restores criticality in the brain, and sleep is like a reset button, he says.
"Being awake and active moves us away from criticality," he says of sleep.
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