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GRKs: Key Communication Switch

This is a news story, published by Yahoo, that relates primarily to GRK news.

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The Conversation

The Conversation

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Science

Science

‘Pac-Man with a ponytail’ proteins regulate everything from night vision to heartbeats – studying what GRKs look like could improve an array of drugs

The Conversation

Summary

Nutrition label

86% Informative

G protein-coupled receptor kinases, or GRKs, play a vital role in maintaining physiological balance.

Around 30% to 40% of all drugs currently on the market focus on these proteins.

Designing drugs that selectively target specific proteins is a difficult task.

Identifying structural differences in different GRKs will help researchers design drugs that only target the GRK of interest.

By combining cutting-edge imaging techniques with decades of research, scientists in my lab and others hope to one day unlock the full therapeutic potential of GRK .

VR Score

86

Informative language

85

Neutral language

48

Article tone

informal

Language

English

Language complexity

56

Offensive language

not offensive

Hate speech

not hateful

Attention-grabbing headline

not detected

Known propaganda techniques

not detected

Time-value

long-living

External references

25

https://doi.org/10.1089/ars.2014.5876 https://www.britannica.com/topic/Pac-Man-1688279 https://doi.org/10.1126/science.1082348 https://www.bio.purdue.edu/lab/tesmer/index.html https://theconversation.com/institutions/purdue-university-1827?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-248298 http://theconversation.com/enzymes-are-the-engines-of-life-machine-learning-tools-could-help-scientists-design-new-ones-to-tackle-disease-and-climate-change-249565?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link1&utm_content=article-248298 https://doi.org/10.1021/acs.jmedchem.7b00112 http://theconversation.com/us?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link-0&utm_content=article-248298 https://www.nature.com/articles/s41401-018-0049-z http://theconversation.com/engineering-cells-to-broadcast-their-behavior-can-help-scientists-study-their-inner-workings-226373?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link2&utm_content=article-248298 https://www.linkedin.com/in/priyankanaik72/https://doi.org/10.1038/s41586-023-06395-9 https://doi.org/10.1016/bs.ai.2017.05.003 https://theconversation.com/visualizing-the-inside-of-cells-at-previously-impossible-resolutions-provides-vivid-insights-into-how-they-work-195873 https://doi.org/10.1038/s41586-021-03721-x https://doi.org/10.1038/nrd3859 https://doi.org/10.1016/j.ceb.2013.10.009 https://www.khanacademy.org/science/biology/cell-signaling/mechanisms-of-cell-signaling/a/intracellular-signal-transduction https://doi.org/10.3389/fcell.2021.687489 http://theconversation.com/seeing-what-the-naked-eye-cant-4-essential-reads-on-how-scientists-bring-the-microscopic-world-into-plain-sight-211666?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link0&utm_content=article-248298 http://creativecommons.org/licenses/by-nd/4.0/https://doi.org/10.1021/cb3003013 https://theconversation.com/profiles/priyanka-naik-2259306?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-248298 https://doi.org/10.1155/2009/327360 https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Supplemental_Modules_(Analytical_Chemistry)/Instrumentation_and_Analysis/Diffraction_Scattering_Techniques/X-ray_Crystallography

Source diversity

9

doi.org www.britannica.com www.bio.purdue.edu theconversation.com www.nature.com www.linkedin.com www.khanacademy.org creativecommons.org chem.libretexts.org

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