Sepsis Quality Measures Questioned

This is a Outcomes news story, published by ScienceDaily, that relates primarily to SEP-1 Compliance news.

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sepsis mandates

ScienceDaily

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Health

New study challenges assumptions about SEP-1 bundle compliance and sepsis outcomes

Summary

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81% Informative

Sepsis, a life-threatening condition arising from dysregulated physiological response to infection, requires rapid treatment to improve survival.

Severe Sepsis/Septic Shock Management Bundle (SEP-1) is controversial because of concern that its rigid protocol does not account for the complexity of patient presentations.

The findings support growing calls from leading professional societies, including the Infectious Diseases Society of America .

Complex Sepsis Presentations, SEP-1 Compliance , and Outcomes . JAMA Network Open , 2025 ; 8 ( 3 ): e251100 DOI: 10.1001 /jamanetworkopen.2025.1100 Cite this article as an article by Chanu Rhee , Sarah E. Train , Steven T. Park , Nicholas M. Mohr , Anne Zepeski , Brett A. Faine , David J. Roach , Emily Porter , Claire N. Shappell , Kamryn Plechot , Laura DelloStritto .