ROS Pathway Aids Chemotherapy Resistance

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cellular ROS levels

Mass General Brigham | Integrated Health Care System

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Science

Mass General Brigham Researchers Identify Mutations That Can Lead to Resistance to Some Chemotherapies

Summary

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89% Informative

Researchers focused on a pathway that harnesses reactive oxygen species ( ROS ) to kill cancer cells.

The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death.

These results, published in Nature , could help pinpoint treatment-resistant tumors.

Mass General Brigham connects a full continuum of care across a system of academic medical centers, community and specialty hospitals, a health insurance plan, physician networks, community health centers, home care, and long-term care services. Mass General Brigham is a nonprofit organization committed to patient care, research, teaching, and service to the community. In addition, Mass General Brigham is one of the nation’s leading biomedical research organizations with several Harvard Medical School teaching hospitals. For more information, please visit massgeneralbrigham.org..

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formal

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English

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not offensive

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not hateful