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Guardian

Guardian

Science

Science

Biologist whose innovation saved the life of British teenager wins $3m Breakthrough prize

Guardian
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83% Informative

David Liu has received the $3m Breakthrough prize for life sciences.

He was chosen for inventing two exceptionally precise gene editing tools, namely base editing and prime editing.

Base editing was first used in a patient at Great Ormond Street , where it saved the life of a British teenager with leukaemia.

First breakthrough came in 2016 when Liu ’s team described base editing, a way to correct single-letter mutations that account for nearly a third of genetic diseases.

Alyssa Tapley , a 13-year-old from Leicester , had run out of options after chemotherapy and a bone marrow transplant had failed to treat her leukaemia.

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English

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