Alzheimer's Proteins Impact Different Tissues

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Alzheimer’s May Be a Whole-Body Disease, Not Just a Brain Disorder

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83% Informative

Scientists have created the first complete cell-by-cell map showing how two key Alzheimer’s proteins— A42 and Tau —impact different tissues in dramatically different ways.

This comprehensive atlas of disease effects may help scientists identify new biomarkers for early diagnosis and develop treatments targeting specific body systems affected in patients.

Sensory neurons involved in vision, audition and olfaction were particularly vulnerable to A42 .

The study’s implications extend beyond fruit flies.

Doctors may need to monitor and address multiple body systems affected by the disease, not just the brain.

The research team has made their comprehensive atlas publicly available to promote further investigation into brain-body connections in neurodegeneration.

This resource provides a foundation for exploring how Alzheimer's affects the entire body.

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