Nup98 Aids DNA Repair Coordination
This is a P01CA265794 news story, published by USC Dornsife, that relates primarily to Anik Mitra news.
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Many DNA repair mechanismsUSC Dornsife
•Science
Science
Protein droplets help protect genome during heterochromatin repair
89% Informative
USC Dornsife study reveals how protein droplets help cells master difficult DNA repair.
Nup98 forms liquid droplets around the damaged DNA, creating a protected space that keeps out the wrong repair tools and helps prevent harmful genetic mistakes.
Discovery could have real-world impact, especially for diseases like acute myeloid leukemia.
Study authors include Chetan Rawal , Colby See, Anik Mitra , Trevor Reynolds , Nadejda Butova and Christopher Caridi of USC Dornsife.
The research was supported by the following National Institutes of Health grants: F31ES036878; T32GM118289 ; P01CA265794 ; R01AR077094 and R01GM124143 .
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